minnesota

CBD: A Brief Introduction

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Interest in cannabidiol, or CBD, has exploded over the past months. Cannabidiol is one of the two main cannabinoids in cannabis, the other being THC. CBD, unlike THC, is not psychoactive and does not produce the same effects as THC. CBD has many different potential therapeutic uses and many patients have found pain relief, reduced anxiety, and improved sleep through CBD. Researchers across the world are currently working to better understand the mechanisms through which CBD works.

Most widely available CBD products are derived from hemp, which was recently legalized in the 2018 Farm Bill in December 2018. Hemp is a variety of Cannabis sativa that, per the 2018 Farm Bill, contains less than 0.3% THC. LeafLine Labs CBD products are not hemp derived, but rather from CBD-rich strains of cannabis. This bill also legalized products derived from hemp federally, such as CBD oils, prompting larger retailers such as CVS and Walgreens to stock CBD products. Hemp production will be tightly regulated, per the Farm Bill, and states are developing their own regulatory frameworks for hemp production as required by the new laws, though these regulations are still in their infancy and are still being developed in many cases.

The wide variety of CBD products available for sale from an ever-increasing number of sources can be daunting. One thing to consider when choosing a CBD product is that LeafLine Labs’ CBD products are subject to testing and regulations that far exceed most hemp-derived CBD products, due to the regulations of the Minnesota Medical Cannabis Program. All LeafLine Labs products must be tested for purity by an independent third party laboratory before they are sold to patients. This ensures that patients receive high quality, pharmaceutical grade medical cannabis.

Additionally, LeafLine Labs CBD products are full spectrum cannabis concentrates. This means that unlike other CBD products, which are often created from hemp distillates containing nothing but CBD. This means that they do not contain the terpenes and other naturally occurring cannabinoids and compounds that LeafLine Labs CBD products do. This limits how much they benefit from the “entourage effect”, the well documented phenomenon of terpenes maximizing the therapeutic effect of cannabinoids.

Cannabidiol therapy is an exciting branch of medical cannabis that needs to be investigated by researchers further to unlock its full potential. If you are a current LeafLine Labs patient, ask your pharmacist if a CBD product could help manage your symptoms. If you are interested in becoming a patient, click here to learn more about becoming certified as a patient under the Minnesota Medical Cannabis Program.

How May Cannabis Help Patients With PTSD?

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Post-traumatic stress disorder (PTSD) became a qualifying condition for the medical cannabis program in Minnesota on August 1, 2017.

PTSD is a mental health disorder that manifests after a traumatic event. Symptoms of PTSD are varied but often include: disturbed sleep, anxiety (specifically when in a situation similar or reminiscent of the traumatic event(s), flashbacks, and more.

In severe cases of PTSD, these symptoms can greatly impact daily life. There is no cure for PTSD, but its symptoms can be managed with medication and therapy.

Medical cannabis can help patients with PTSD by decreasing anxiety, improving sleep, decreasing nightmares, and helping to reduce avoidant behaviors.

LeafLine Labs pharmacists are experienced in treating patients with PTSD, and many of our patients who are currently being treated for the disorder have achieved great symptom relief. Our goal with medical cannabis therapy is to help manage the symptoms of PTSD and help improve patients’ quality of life as much as possible.

How May Medical Cannabis Help Cancer Patients?

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Tangerine, our high-THC and low-CBD formulation, is our most commonly used medication for cancer patients.

THC often gets a bad rap, but provides a lengthy list of therapeutic benefits such as: decreasing pain, improving appetite, increasing weight gain, and improving sleep. THC is also known for its anti-nausea, anti-emetic (vomiting) and anti-anxiety properties.

The small amount of CBD that is in this product has anti-inflammatory properties. CBD helps to improve the anti-nausea, anti-emetic and anti-anxiety properties of THC, which are helpful in progressive diseases as well as during and after chemotherapy.

THC and CBD have also shown to have anti-cancer properties, similar to chemotherapy but without the systemic damage. This has not been clinically proven, as it is all based on patient reports, but is promising nonetheless.

At LeafLine Labs, we see a variety of patients with cancer, ranging from pediatric to elderly, with a wide variety of diagnoses. We have seen many cancer patients who have experienced decreased nausea, healthy weight gain, pain management, improved sleep, decreased anxiety levels and who have been able to decrease their use of narcotics, sleep aids, or anti-nausea medications.

Read how medical cannabis from LeafLine Labs has helped Char after her stage 4 metastatic breast cancer diagnosis on the blog.

Medical Cannabis, Intractable Pain & Cancer: Lisa's Story

Lisa of Apple Valley, Minnesota, is a mother to twin daughters, a wife, and Marriage and Family Counselor. Her husband, Mark, is a stay-at-home father. Together, they have worked hard to build the life they have always dreamed of.

Lisa had a lumpectomy when she was just 17. At age 22, she was told she had rheumatoid arthritis; the pain was so profound at one point that she was confined to a wheelchair. Years later she was diagnosed with metastatic breast cancer and Hodgkin’s lymphoma.

“I remember looking at my nightstand and my Oxycodone was half full. Half full, not empty,” Lisa recalled. “And I panicked. I thought, I need more. And I wasn’t even close to being done with it. It was just that fear the pain would come back.”

To treat the pain, she tried everything. From surgeries, to infusions, to a long, convoluted list of medications and prescription painkillers. Nothing worked. As far as the pain medications went, they only sedated her and left her in a constant fog, but they didn’t help with the pain.

“The days didn’t look like anything,” she remembers. “My days blurred into one another. I wanted to be asleep, I didn’t want to be present.”

Her days consisted of short periods of work and restless sleep. After her two beautiful daughters, Lily and Lucy, were born, she remembered crying a lot. The pain kept her bedridden most of the time and the painkillers left her feeling numb and exhausted. At the time, she didn’t have the physical strength or energy to participate in her girls’ lives the way she wanted to. It broke her heart.

Her husband, Mark, has stood by her side through all of it and took care of Lisa and their girls. He stayed at home during the day to take care of Lily and Lucy and lovingly attended to Lisa’s every need; he would often clothe her, help her with her hair, and fetch her a glass of water when she couldn’t get out of bed. “His days never ended,” Lisa shared, “He was, and is, my rock.”

As a last resort, she decided to enroll in the medical cannabis program.

Going into her first appointment at LeafLine Labs, Lisa and Mark were both weary. She had taken an unconventional path to find a certifying physician for the program and it all still felt surreal. They were both pleasantly surprised at the professionalism, compassion and kindness they were met with at her initial consult; it was unlike any other medical experience she had ever had.

“The system works so much better than any other system we have. “Hey, what does your pain look like? Where, when is this hurting you? This matches you,”” Lisa explained, “You don’t ask those questions with opiates. It went from being a shady, weird experience to oh my gosh, this is new age.”

Lisa and her pharmacist have worked together to find a combination of Tangerine and Heather that provides her with just the right amount of relief. She still has flare ups of pain and struggles with asleep from time to time, but her quality of life has increased exponentially.

“I think it was the first time I really rested well and was able to go to sleep,” Lisa recalled of her first dose.

The opioid fog has been lifted and Lisa feels better than she has in over a decade. Although she still occasionally uses opiates for flare ups of breakthrough pain, she has reduced her use of prescription painkillers by about 75 percent. Her need for morphine and benzodiazepines has been completely eliminated.

Before medical cannabis, she believes her quality of life was close to a 2 on any given day. Now, she experiences days, more often than not, that feel like an 8. Her husband, Mark, agrees; before medical cannabis, anything physical - whether it was getting her food or water, or helping her to get up to go to the bathroom in the middle of the night - he would have to help her with. Now, she can do things on her own once again.

“I’m the one that bathes them now,” she gushed. “There’s a sense of pride to that because before, I couldn’t.”

On Saturdays, Lisa and her family go on outings. Now that they don’t have to bring her wheelchair everywhere and Mark doesn’t have to push her, they can do more, they can go farther. They visit amusement parks, apple orchards and places like the zoo.

Aside from helping Lisa find relief from various sources of pain, Lisa believes medical cannabis has helped to bring her family closer together. “We learned really early on in life that things can be taken….the people, your family, that’s all of it [that matters],” she said. “This program has impacted my family. [My husband] can pay more attention to my daughters if he doesn’t have to take care of me….It makes me happy. It has changed my life."

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Medical Cannabis, Seizures & Autism: Hiroki's Story

Hiroki of Cottage Grove, Minnesota, is 8 years old. Cognitively, he has progressed to approximately age 2. His smile can light up even the darkest of rooms. He enjoys spending time with his family and playing with his younger brother, Taiyo. He loves to walk with his parents, grandma or his professional au pair to the mailbox each day. Hiroki becomes giddy with excitement when he knows it’s time; weather permitting, they venture past the mailbox and toward his favorite fence so he can run his hands along it and then take a long walk around the neighborhood.

At the time of his diagnosis at 1 years old, Hiroki was 1 of 600 in the world known to have Phelan-McDermid syndrome (PMS), a rare genetic condition commonly characterized by intellectual disability of varying degrees, delayed or absent speech, low muscle tone, seizures, and motor delays.

Around age 3, Hiroki was diagnosed with epilepsy and autism spectrum disorder, which are both common characteristics of PMS. He also has a number of other conditions such as asthma, dysphagia, autoimmune dysfunction, and hip dysplasia.

Misa and Dan, Hiroki’s parents, characterize their lives as “Before” (Before Medical Cannabis) and “After: (After Medical Cannabis) because of the stability medical cannabis has brought to the family.  Before medical cannabis, most of their family’s days were stressful, repetitive and rushed.  Unable to stay at home because of Hiroki’s anxiety and need to be “out and about,” they would be out the door by 8:30 am and back by noon for Hiroki’s nap.  And then, they’d be out the door again by 3 pm and home around 7 pm. On every outing, Hiroki would get upset and cry if they took a left rather than a right. Hiroki himself was stressed and anxious, and he would have a hard time sleeping at night.

Before Hiroki’s seizures were controlled with the help of medical cannabis, Misa and Dan became unofficial detectives and nurses.  Hiroki is nonverbal and does not sweat, which is characteristic of children with his diagnosis and makes it difficult to determine how he is feeling. For most of his life, Hiroki’s parents have lived in fear. “It’s like we play detective,” Misa explained of his seizures, “We’re always trying to figure out when the next big one is coming.”

Every 2 weeks to 2 months, Hiroki would experience grand mal seizures so critical that he would often stop breathing. His last seizure was so severe that it left him unconscious for more than 30 hours. At one point in time, Hiroki was being seen by 22 specialists and taking up to 8 different medications per day. His parents were determined to find a more holistic tool for them to help treat symptoms of his diagnoses.

Since starting medical cannabis (the “After”) 3 years ago, so many doors have been opened for Hiroki. He has not had a single grand mal seizure since. Although he still becomes anxious with changes to his routine, his cognitive speed and functioning have increased and his ability to cope with daily changes has improved significantly. He is more aware and present, and he’s beginning to show more interest in interacting with family and peers. He can spend time comfortably at home, school assignments and walk on the treadmill. “Team Hiroki” has been able to teach him how to use his iPad to communicate simple sentences like “I want to eat PB&J”--one of his favorite snacks.  Misa and Dan are grateful for the simplest of “typical” family routines: eating a family meal together at home, playing games as a family, and dancing together in the living room.  Within the community, he can go to horse therapy in the summer, adaptive snow ski in the winter and family golf outings. Visits to the pharmacy and the number of prescriptions he takes have drastically declined, which his parents are ecstatic about. He now actively sees only three specialists and is taking 2 medications.

Misa and Dan feel like he is making cognitive gains each day and they have been able to potty train him to some degree, which is extremely rare for children with his condition.

Hiroki can now scoot down the stairs after waking for the morning or from his afternoon nap. He can also drink from his sippy cup, a new freedom for Hiroki that he has never experienced before.

His mother believes Hiroki’s, as well as the entire family’s, quality of life has gone from a 1 to a 10 since he began medical cannabis. “There is nothing that has changed our lives more significantly than the availability of medical [cannabis],” she shared.

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Medical Cannabis, Seizures, Autism & Intractable Pain: Lucas's Story

Lucas of Lakeville, Minnesota, is in many ways your typical 18-year-old boy. He loves girls, Will Ferrell movies, and sports--baseball is his favorite. He also loves some good potty humor, Elmo, and spending time with his big sister.

At age 3, Lucas was diagnosed on the autism spectrum and with cerebral palsy. Around the same age, his parents were told that he also suffered from seizures.

In addition to the seizures, Lucas would often inflict harm on himself or others. He was anxious, restless and would often struggle to get restful sleep. Some of Lucas’s behavioral tendencies has made it hard for his family to spend time out in their community. “Autism is our life,” his mother explained. Lucas and his family have spent many days at home watching TV.

To help manage symptoms and the progression of his diagnoses, Lucas was prescribed a number of different medications. Unfortunately, most of those medications came with side effects that required even more medications to manage them, adding to an already lengthy list of prescriptions. Nearly two years ago, Lucas’s cholesterol and triglyceride levels were so high that his doctor prescribed him Fenofibrate, a common drug for his condition but uncommon for someone so young.

After they had exhausted what seemed like every treatment option, Lucas’s physician recommended enrolling in the medical cannabis program in Minnesota. Interested in lowering the number of prescription medications he was taking and finding a more natural treatment option, his parents were immediately interested.

Since Lucas was young, Olivia had researched and kept in mind the possibility of medical cannabis as an alternative for him, but for years it wasn’t legal and she still had her hesitations once the program started in 2015. After Lucas’s physician certified his condition and they enrolled through the Minnesota Department of Health, it took nearly a month for his parents to decide to make an appointment at LeafLine Labs.

Now, Lucas experiences relief from pain and seizures without the long lists of side effects that prescription medications left him with; they have been able to wean him off most of his pharmaceuticals.

Lucas is mostly nonverbal and prefers not to be touched most of the time, but one of the words he uses frequently is cream. When he experiences pain from scoliosis, for which he is undergoing a spinal fusion surgery in mid-July, he will ask for his cream and stand perfectly still while one of his parents rubs the Heather Topical Gel Cream on his back. “It’s pretty incredible,” his mother remarked.

“As soon as the cannabis was given to him, the hitting of himself stopped. The violent outbursts with us stopped. It was like night and day,” Olivia shared. “I was really expecting him to start speaking and, you know, write his own name and all of these other miracles. I know they will happen someday, though. Just the fact that he stopped hurting himself was enough.”

Olivia describes Lucas as being more self-aware. “I feel like he’s in our world more than he used to be,” she said.

Lucas is thriving in his autism program at school and he is expected to graduate when he turns 21. He can sit in class, focus and not get distracted by what’s going on around him. His parents feel as though he’s learning and making cognitive gains more so than ever before and they haven’t noticed any seizures since he began taking medical cannabis.

He is more interested in participating in the world around him. The other day, his face lit up when his sister entered the room, his mother shared, whereas before he may not have even noticed.

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This past February, Lucas attended his second Night to Shine prom night experience, an event sponsored by the Tim Tebow Foundation for people with special needs age 14 and older. In contrast to his first time prior to medical cannabis, this last prom was a night-and-day difference. He wore his first tuxedo, he participated in activities and interacted with his peers, and he seemed more focused. “He really seemed to enjoy himself,” Olivia shared.

Lucas’s parents are amazed every day by the improvements in health, mood and behavior they’ve seen in their son, and they are eager to witness even more progress once he begins to heal from his spinal fusion surgery in July.

Looking back to the beginning of Lucas’s journey with medical cannabis, Olivia’s only regret is not making an appointment immediately. “It could have been one more month that he had this medicine,” she said.
 

Intractable Pain, Obstructive Sleep Apnea & Medical Cannabis: Tony's Story

Meet Tony, a LeafLine Labs patient who lives in Apple Valley, Minnesota. He is your not-so-typical ‘retired’ (as he likes to call it) 25 year old. He graduated from Augsburg College with a degree in Management Information Systems. He’s sharp, smart, and has a great sense of humor. A self-proclaimed music critic, he runs his own blog where he shares his thoughts on the best and worst of the industry. He enjoys going to movies, playing video games, and spending time outside as much as he can.

Tony grew up walking, running, and participating in all the activities of a typical childhood. When he was 4 ½ years old, he started showing signs of Duchenne Muscular Dystrophy (DMD), a disorder of progressive muscular weakness most commonly found in boys. To help manage symptoms of DMD, Tony began taking steroid injections.

Although the steroids helped to slow the progression of DMD, they did not come without side effects. Most notably, he stopped growing around age 12. He also experienced cataracs, high blood pressure and often crippling anxiety. His appetite was small, at best, most of the time. He was later diagnosed with Obstructive Sleep Apnea.

Tony’s calf muscles were the first part of his body weakened by DMD, which caused him to walk on his tiptoes. In middle school his overall mobility was quite affected. By high school Tony was using a wheelchair.

The combination of side effects from steroid injections, the chronic pain from sitting in a wheelchair all day, and the stress and physical toll a lack of sleep takes on the body led him to to enroll in the medical cannabis program here in Minnesota in November 2016.

Prior to enrolling, Tony and his family--mom, dad, and brother--took part in petitioning the addition of Intractable Pain to the medical cannabis program in Minnesota. They’ve attended rallies at the capitol and consider themselves advocates for cannabis as medicine.

Tony and his parents struggled to find a physician who would certify his condition. Eventually, they were referred to a physician who was willing to help and was actively certifying patients for the medical cannabis program. “It was challenging. Worth it, but I wish it was easier,” his mother, Carol said.

Since beginning cannabinoid therapy with medicine from LeafLine Labs, Tony’s life has been changed for the better. His quality of life, as well as his family’s, has increased significantly. His appetite is back, he has real, lasting pain relief, and his anxiety is manageable. He can sleep through the night. He can spend longer periods of times doing the things he loves, and he can also spend more time in his wheelchair without his back hurting. He is completely off steroids. “It makes everything better,” Tony said.

As parents and caregivers, Carol and Steve, have found an incredible amount of relief in seeing the changes in their son’s mobility, mood, and overall quality of life. His diagnoses have helped them, as well as his brother, appreciate their own health and not take anything for granted.

Tony and his family work every day to embrace and embody the adage “Live life to your fullest," and medical cannabis has been a key component in allowing all of them to do just that. One of the perks of his situation? “Handicap parking,” Tony joked. Remember that great sense of humor?

Tony’s piece of advice for anyone considering enrolling in the medical cannabis program here in Minnesota: “Don’t pass it by without giving it a chance…”

 

Summer 2018 LeafLine Labs Patient Care Center Update

May 24th, 2018

In order to best serve and care for you, our growing community of patients, we have decided to adjust our hours of operations at our patient care centers across the state. As new conditions and patients come to the program, we have a responsibility to you, the LeafLine Labs team, and the State of Minnesota to operate efficiently and responsibly. In alignment with the shift in hours and to accommodate increased demand, we are no longer able to accommodate walk-ins for consultations, which means all consultations will need to be scheduled on an appointment-only basis going forward.

Starting on June 11th, 2018, LeafLine Labs patient care centers in Eagan, Saint Paul and St. Cloud will have updated hours, which will be as follows:

Monday-Saturday: 9am to 5pm
Sunday: closed

Hours at our Hibbing patient care center will remain the same:

Monday-Thursday: 9am-5pm
Friday: 9am-3pm
Saturday: 9am-1pm (every 1st and 3rd Saturday)
Sunday: closed

Our mission and driving force behind everything we do at LeafLine Labs is to provide exceptional care for our patients, and we believe these changes are in alignment and full support of that mission.

If you have questions, comments, or concerns, we are always just a phone call away. Please call us at 1-844-LEAFLINE.

 

Sincerely,

The LeafLine Labs Team

 

Medical Cannabis in Minnesota Proves Successful in Fight Against Opioid Epidemic

As a physician with a clinical career spanning 14 years, I’ve been both trained and compelled to learn more and strive to care better. As such, upon recognizing the practitioner’s role in a multifactorial, pervasive, complex, systemic, escalating healthcare problem that has become formally acknowledged as America’s devastating prescription opioid epidemic, and federally acknowledged as a “Public Health Emergency,” I was inspired to pursue education and innovation over inertia and inaction.

For the last two years, the CDC has published data suggesting decreasing life expectancy despite increasing healthcare expenditure in the U.S. Opioids are now responsible for over 42,000 U.S. deaths annually and prescription drugs have become our nation’s leading cause of preventable death. More of us are dying from opioid overdoses than from either car accidents or gun violence.

Emboldened with the knowledge that our existing pharmacopeia was offering too little for some, while concurrently too much for many, I stepped away from traditional clinical practice to found LeafLine Labs, one of only two registered manufacturers and providers of medical cannabis and associated care in Minnesota.

Medical Cannabis has a documented history of medicinal use and success in the management of pain and other symptoms and conditions for the past 5,000 years, without a single case of death ever documented or attributed to acute toxicity or overdose.

Since the launch of the state’s program three years ago, over 5,000 LeafLine Labs patients have received our life-changing medicine, with ZERO serious adverse health events or hospitalizations attributed to our care, and countless stories of success. Our medicine has proven safe, consistent and effective, with patients experiencing fewer seizures, fewer symptoms, fewer side effects, and more sleep, more quality of life and more hope. And while we are pioneering prospective studies that will show the undeniable impact of medical cannabis, the compelling data we have observed to date is tangible evidence that this medicine is already impacting and saving lives.

The research team at LeafLine Labs has taken the first step to quantitatively confirm what we have anecdotally seen as professional caregivers over and over—medical cannabis is an appropriate medicinal treatment option for both pain control and for tapering patients off of opiates. A retrospective chart review of 100 LeafLine Labs patients (50 males, 50 females, age range 23-91, randomly selected) who qualified for Minnesota’s program due to intractable pain and were on opiate medications upon their initial consult has recently been completed, with more to follow.

The results are more than impactful. They are monumental as evidential support to confirm that medical cannabis is a safe, effective way to manage and alleviate pain. We found that 90 percent of patients had a decrease in their self-reported chronic pain level after 30 days of treatment (a result that was successfully maintained through 90 days) and 35 percent of patients had a self-reported decrease in their opiate use and/or had discontinued opiate use entirely after 30 days of treatment (a result that was similarly maintained through 90 days). The most common additional benefits cannabis provided, in addition to pain reduction, were sleep improvement (49 percent) and anxiety relief (26 percent). These results are nothing short of a miracle for patients who have been dealing with pain, dependence, addiction and debilitating side effects from opioids for years.

In an enlightening and now replicated 2014 study published in JAMA, the mere existence of a responsibly regulated medical cannabis program within a state allowing chronic or intractable pain as a certifying patient diagnosis correlated with a 25-33 percent reduction in prescription opioid overdose deaths. With responsible medical advancement, thousands of lives have already been saved, and more progress will follow.

As a profession that places patient well-being as our highest priority, we must accept responsibility to re-examine prescribing practices. That means embracing cannabis for the medicinal option it has always been and responsibly replacing its perceived stigma with medical relevance, scientific legitimacy, and most importantly, effective and compassionate care.

The worst public health crisis of our time may tragically have been brought about by modernized Healthcare and the practice of medicine therein, but it may similarly be responsibly addressed and eradicated with bold actions by the same.

By Dr. Andrew Bachman, LeafLine Labs Founder, CEO and Chief Medical Officer

Medical Cannabis & Cancer: Amy's Story

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On June 1, 2016, Amy’s life—and all of her loved ones’ lives—changed forever; she was diagnosed with stage 4 metastatic breast cancer.

Amy—a wife, loving mother and entrepreneur who enjoys eating the incredible food made by her wife—lives in Saint Paul, Minnesota. She has started 2 businesses with her wife: Lucille’s Kitchen Garden and Midwest Pantry.

The first 6 months of treatment were especially trying not only physically, but mentally and spiritually as well. Amy took “really hard, tough” drugs, as she describes, and the chemotherapy would confine her to bed for 5 to 7 days each time. Throughout, she found herself anxious, nauseous and sleeping the majority of the time.

Although the combination of chemotherapy and steroids reduced the size of her tumor, it also destroyed her body. A torn rotator cuff left Amy with a limited (at best) range of motion in her shoulder and constant, excruciating pain. After 4 agonizing months of searching for a medication that would bring her relief with no avail, she was admitted to the hospital. Even once she was admitted, Amy went through trial after trial of opioids to find the one that worked best for her body before she could be released.

Having followed the industry and hearing stories of success from friends in her community, Amy inquired with her social worker and palliative care staff about medical cannabis as a treatment option. Once she received approval of her physician and was added to the state registry, she got her confirmation on a Friday and the next Monday she met with a pharmacist at LeafLine Labs.

Now, Amy has gone from taking 17 pills per day to only 4. Chemotherapy no longer robs Amy of precious time spent doing things she loves with the people she loves, like taking vacations to Costa Rica—which would not have been realistic before she began treatment with medical cannabis.

According to Amy, her experience with LeafLine Labs and medical cannabis has been very positive and amazing. She appreciates the kindness and willingness to help from the staff at her patient care center. The medical cannabis not only helps her with side effects of chemotherapy and the pain that comes with her diagnosis, but with her anxiety, depression and PTSD as well. “…this has been a life saver for me and has raised my quality of life,” Amy shares, “I appreciate the simplicity of the cannabis with no side effects.”

Last summer, she was in such a fog from the chemotherapy that she doesn’t remember much of anything that happened. This past summer, medical cannabis helped to ensure that Amy could function in comfort and enjoy time cooking with her wife, playing with her daughter, and enjoying life’s little pleasures. She has her life back, she claims. She has finally found relief.

Pharmacists' Role in the Minnesota Medical Cannabis Program

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Unlike most other states, Minnesota’s Medical Cannabis Program is overseen by the Department of Health and mandates that MN licensed Pharmacists meet with patients to develop a plan of care.  Product selection and dosing are determined by the Pharmacist in consultation with the patient.

Whether you are a prospective patient or you are simply curious about the patient experience at LeafLine Labs, we have consulted with our Pharmacy Team to provide insight on the role of pharmacists in the Minnesota medical cannabis program.

When you first come to a LeafLine Labs Care Center, you will meet with a Patient Care Coordinator to fill out initial paperwork. A Pharmacist then conducts an Initial Consult, which can last 30-45 minutes. As part of the Initial Consult, Pharmacists gather information from you (or a caregiver/guardian). We discuss past medical history, all current medications including other cannabis use, current and past diagnoses, any treatments for your qualifying condition, as well as other conditions or symptoms presently of concern. We screen for elements in past or current history that may warrant special consideration in LeafLine Labs medication therapy initiation, such as drug interactions or other medical conditions. Information you provide to the Minnesota Department of Health on a Self-Evaluation Survey is incorporated into our internal LeafLine Electronic Health Record, and reviewed with you.

After a thorough consultation, you and the pharmacist agree on an initial plan of therapy designed to meet your goals for symptom relief.  We educate you on all aspects of how to use your new medicine, as well as what to expect for effects and side effects. You will purchase your medicine at the end of the consult, right from the dispensary in the Care Center.

Generally, we like to see you for a Return Consultation after about 2 weeks of using Medical Cannabis, so we can “fine tune” the medication plan to best help you.  From there, you and the Pharmacist have an ongoing relationship for follow-up consultations and dosing adjustments as needed.

Medical Cannabis, Fibromyalgia, & PTSD: Kim's Story

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For Kim of Benson, Minnesota, it happened all at once. In the early winter of 2015, her father—who she adored—passed away and along with him, the remainder of her support system. She was devastated. Shortly after, she was diagnosed with shingles which took the chronic, widespread pain she lived in every day from fibromyalgia and multiplied it; the pain was horrific.

Kim, who has 5 dogs, 7 cats and several other four-legged friends (as well as two-legged), has been an animal lover since day one; when she was younger, she did not have dolls—she had pets. Raising and taking care of animals is a passion she shared with her father. She also loves to spend as much time outside as possible when she’s feeling up to it.

Kim was diagnosed with fibromyalgia back in 1996 and in 2015 when the shingles came, a pain she never could have imagined accompanied it. Although the rash from the shingles virus only lasted about 2 weeks, Kim suffered permanent nerve damage that she will live with for the rest of her life. She tried every solution her doctor recommended—from anti-seizure medications, to opioids and topical medications—but nothing worked. “I tried all of the heavy stuff, and it didn’t touch it. It didn’t even touch [the pain].”

In January 2017 when the pain was so excruciating and debilitating that she had to give up the deer she and her father had raised – all 43 of them – she felt as though she had nothing left to live for; there have been many days when the pain led to her question whether she wanted to live any longer.

“It’s very emotionally painful as much as it is physically painful. People just don’t understand [my situation],” Kim says, “…Take something that you’ve lived for and then never do it again. I don’t know how else to explain it.”

Once Kim’s doctor recommended she look into medical cannabis, she did not hesitate; medical cannabis was her last resort. Once her condition had been certified and she was added into the state registry, she made an appointment at LeafLine Labs.

It took approximately a month for Kim to find her therapeutic dose but now that she has, she has started to feel better than she can ever remember—that’s how long she has been living in pain.

“It’s a necessity is what it is now,” she explains, “To me, it’s no different than somebody that needs heart medication. If you don’t take this, you’re going to die.”

Before medical cannabis, she describes her quality of life, on a scale from 1 to 10, at 1. Now, with medical cannabis there are days where she feels so good, so normal, that she forgets to take her dose. She has been able to stop taking all of her prescription pain killers and is now free of all the side effects that came with them.

“I don’t even take Aspirin or Ibuprofen [for the pain]. At all,” she shares.

Kim feels as though the medical cannabis helps to relieve all pain from the nerve damage caused by shingles and she has yet to experience any side effects from her medicine. She truly believes that if her parents had been able to use medical cannabis when they were sick that their quality of life would have been drastically better before they passed. Medical cannabis helps Kim to care for her pets, spend time outside, and navigate her days in comfort; the relief she experiences gives her hope for the future.

Medical Cannabis, Intractable Pain, & PTSD: Kristina's Story

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For Kristina of St. Cloud, Minnesota, her diagnoses of PTSD, Fibromyalgia, and a traumatic brain injury (TBI) brought a wave of relief for her and her loved ones. For decades, she did not know what was wrong with her; numerous doctors told her she was perfectly healthy and test results seemed to tell the same story.

Growing up, Kristina experienced bullying and harassment that eventually caused her to block out any memories of her childhood before age 10. When she was in high school, she started seeing a counselor to help her work through the feelings she was experiencing. Unfortunately, counseling was unsuccessful in bringing relief and as alternative treatment she was introduced to antidepressants.

During the decades before she was diagnosed, she was prescribed more pills than she could count from her psychiatrists and pain specialists, though the pain relief she experienced was not nearly significant enough to outweigh the side effects. In 2004 while taking her three children for a walk, Kristina and her family were struck by a distracted driver. Luckily, there were no fatalities, but Kristina and her youngest son sustained TBIs—both of which were not correctly diagnosed until years later.

Come 2011, Kristina was diagnosed with PTSD and it wasn’t until 2013—nearly 10 years after being struck by a car—that she was diagnosed with Fibromyalgia (which they believed was in-part due to PTSD) and a TBI. Putting a name to her conditions meant being able to pursue a more targeted treatment regimen, but her health care practitioners continued to prescribe pills—she overdosed several times.

When Kristina inquired about medical cannabis as a treatment option, her neurologist at a major health care system in St. Cloud refused to continue seeing her. This sent her into a dark spiral of depression and she embarked on a year-long journey to find a physician who would certify her for the medical cannabis program. There were times when she believed taking her life was the only way to find relief from her own thoughts and pain.

As she describes it, she lost herself. Kristina was in a constant fog. She was confined within the walls of her home, unable to participate in the world and to be the mother her children needed and she so desperately wanted to be. She could not put on makeup, shower, do the dishes, or even wear shoes because of the pain flares that come with Fibromyalgia. When she was able to muster the strength and will to attend family events, she would be bed-ridden and recuperating for weeks at a time afterwards.

Exhausted and in dire need of something that would improve—and quite frankly save—her quality of life, she was able to find a physician who would certify her for the medical cannabis program in December 2016. Once approved in the registry, she made an appointment at LeafLine Labs.

Although her qualifying condition was intractable pain, Kristina shares that she has seen the biggest improvements with symptoms related to PTSD. She is appreciative of how willing the pharmacists at LeafLine Labs are in treating all of her conditions, not just those that qualified her for the program.

Once she began using medical cannabis, it took about 10 weeks for her to be weaned off her pain medications and 5 months until she was off everything, including the medications she was prescribed to treat PTSD. “It was really hard,” she admits.

She felt like giving up many times due to withdrawals, pain and a racing heart, but she remained persistent and patient. Kristina’s loving husband, Byron—as well as her family and friends—were and continue to be supportive, compassionate, and understanding of her journey toward an improved quality of life. Today, she isn’t entirely healed and still must deal with symptoms from her conditions, but both she and her husband agree that her progress has been life-changing.

Kristina is now off of all pain killers and prescription pills she was prescribed for PTSD, Fibromyalgia, and her TBI. Not only is she willing, but also able, to leave her house again. She can do the dishes, put on her makeup, and wear shoes—at least for much longer periods than before. When she is able to attend family events, she can recuperate much faster and isn’t confined to her bed for weeks at a time. “I feel like myself once again,” Kristina says.

Before medical cannabis, she says she had no quality of life at all. Now, each day her quality of life is, on a scale from 1 to 10, anywhere from a 9 to 10. As for her pain, which used to be a 9 or 10 on any given day, it has been reduced to a more manageable range of 1 to 3.

Most importantly, Kristina can once again be a mother to her children. She can take her youngest son, who has been diagnosed on the autism spectrum and who has a fear of dogs, on walks outside. “I found myself. I’m back,” she gushes.

Last year for prom dress shopping, Kristina’s daughter was accompanied by her aunt because Kristina’s conditions prevented her from comfortably leaving the house. This spring, Kristina is overwhelmed with joy that she will be able take her daughter shopping to find the perfect prom dress; she attributes this monumental mother-daughter-first to medical cannabis from LeafLine Labs. Kristina, her husband, and her support system of friends and family are hopeful and excited to see what progress will be made as she continues to use this safe, natural medicine.

Medical Cannabis, Migraines, & Cluster Headaches: Mike's Story

“It feels like someone is pushing your eye out,” says Mike of Lakeville, Minnesota, on describing the pain he endures from cluster headaches. “Don’t worry, my condition isn’t contagious,” he jokes.

Mike is a husband, a father of two beautiful daughters and two dogs, and an avid runner. He has lived with vertigo off and on for most of his life, but it wasn’t until August 2016 that he started to experience excruciatingly painful cluster headaches and migraines. Once he was diagnosed, he spent most of the first four months confined to dark rooms, head on ice, with oxygen tanks ready at his side to help bring down the pain.

In the following months, Mike experienced cycles of pain so extreme and debilitating that he could no longer work or carry on with normal day-to-day functions. To treat the pain, Mike’s physician prescribed him Verapamil. Although the medication was very effective, he experienced low blood pressure and a low heart rate and it often left him feeling out of breath. Mike attempted to lower the doses he was taking, but the headaches would get worse each time. Looking for another option, his physician recommended he try Topamax—a ‘nasty, nasty’ drug as Mike describes it, “It’s almost like you’re on heroin walking around,” Mike says, “it really dumbs you down.”

Other prominent side effects from his medications included slurred speech, tingling throughout his entire body, fatigue and a foggy state of mind.

When Mike’s vertigo was at its worst, he decided to pursue self-medication. As an alternative to smoking—he didn’t care for the way it made his lungs feel or some of the other side effects—he began to make cannabis tea. When the tea helped, it would bring his pain and nausea, on a scale from 1 to 10, down from 8 to 4. “That’s the difference between being stuck in bed or being able to go out and cut the grass,” Mike explains.

The issue with making his own tea was that he was never quite sure what he was getting—what chemicals or fertilizers were used or what combinations of compounds were in the cannabis. Sometimes, he would have one cup and he would experience just the right amount of relief; other times, he would have one cup and would be over-medicated and confined to bed—the outcome he was trying to avoid in the first place.

Looking for more consistency and reliability in his pain management with the cluster headaches, Mike decided to pursue enrolling in the Minnesota medical cannabis program. In search of more information before making an appointment, Mike called LeafLine Labs. He remembers everyone he spoke to as helpful, professional, polite and kind, which gave him the confidence he needed to make his decision. He scheduled an initial consult with a pharmacist at LeafLine Labs.

Today, Mike’s pain generally ranges anywhere from 3 to 5, rather than 7 to 9. On his best days, medical cannabis helps to dull the pain from 2 to 3—which in Mike’s book is considered 0. With 3 on the pain scale, Mike can still do work around his home or spend time with his family, rather than being out of commission and unable to participate in his own life. The other benefit that Mike enjoys with the cannabis is the ability to sleep. When the headaches were at their peak he was sleeping 2 to 3 hours per night. He now regularly gets 8 hours. “The cannabis, it’s been huge. It’s just been huge,” Mike says, “It didn’t cure me or anything like that, but it suppresses the pain… Cannabis is one of my tools in this fight.”

Medical Cannabis, Muscle Spasms, Intractable Pain, & PTSD: Ed's Story

Meet Edmund (Ed), a Marine veteran, husband, father, grandfather, and patient at LeafLine Labs. Ed is a medically retired VA Field Examiner who enjoys hunting, fishing, gardening, and spending time with his wife and two dogs. Ed has been diagnosed with various forms of intractable pain, muscle spasms, and PTSD.

For decades, Ed lived with excruciating pain from a service-related injury (USMC 1979 to 1993), in his neck (cervical spine) and his lower back (lumbosacral strain). In the past, he was only able to sleep four to six hours a night because of constant neck pain or numbness in his arms—which started as radiculopathy and progressed into serious pain over time. In addition to his pain, he began to develop knots half the size of a fist on either side of his low-back which was extremely uncomfortable and painful.

Ed decided to undergo neck surgery in 2008, which was not a success, and had subsequent cervical fusion in 2015, which was also unsuccessful. Ed also had surgery on his lower back in 2012, to no avail. Treatment that followed was conservative, including pain meds when needed, anti-inflammatories, and physical therapy - but these all simply masked the pain, rather than address the underlying reason for it.

With his traditional methods of treatment not providing relief or the results he desired, he decided to research and then enroll in the Minnesota Medical Cannabis Program. Since his first appointment at LeafLine Labs, Ed has been able to drastically improve his quality of life with the help of medical cannabis. Edmund says that he has found 70-80 percent relief from muscle spasms in his back and that, “As for my back resolution, with regards to pain, that’s all gone! I’m able to get up and get around and do things I couldn’t do before. There is benefit [to this medicine]. I’ve seen it. I feel it. What more can I tell you?”

Medical Cannabis, Tourette Syndrome, & Autism: Kyle's Story

Just before turning 3, Kyle Jr. was diagnosed on the Autism spectrum. Within the last year, Kyle, who turns 8 this summer, was also diagnosed with anxiety, ADHD, and Tourette Syndrome. Having tried 8+ different medications that either caused too many side effects or had no effect at all, his parents felt a wave of relief when they found out his Tourette Syndrome diagnosis qualified him for the medical cannabis program in Minnesota; they were out of options, and they so badly wanted to find relief for their eldest son.

Almost entirely non-verbal, Kyle Jr. would often get frustrated when he wasn’t able to communicate what he wanted or how he was feeling. “He was so angry all of the time,” his mother, Kassidy, remembers.

Sometimes, he would harm himself or others. The constant tics in various forms paired with anxiety and aggression left Kyle with little quality of life. Before medical cannabis, Kyle Jr. spent most of his time on the couch—playing or interacting with others was a rarity. Aside from bathing, there were few times he willingly left the couch—it was his safe spot. When he would leave, he would need to have someone’s hand to hold for even the simplest of tasks, like going to the bathroom. Car rides were hard, and going to the grocery store or any other kind of shopping was nearly impossible to do as a family.

Kassidy was pleasantly surprised at how quick and simple it was to complete the enrollment process and become a caregiver for Kyle. Once certified by a health care practitioner, it was only a matter of days until Kyle’s first visit at a LeafLine Labs patient care center. His family began to see a difference within days of his first dose of medical cannabis.

Today, 7 months after adding cannabis to Kyle Jr.’s health care regimen, his parents are astounded at the difference the medicine has made in not only his life, but their entire family’s. Kyle Jr.’s therapy team, dentist, and primary care physician have all remarked at the improvement in his behavior; during his last appointment to the doctor, he went with the nurse by himself for the first time to have his height and weight checked. His communication skills are vastly improving, he’s learning new letters and words, and he’s beginning to ask questions. His tics are less severe and less frequent. Harming himself or others is now rare. He plays. He smiles once again. He’s calmer. Most importantly, he’s joyful.

Kyle’s parents have a renewed sense of hope and are excited by the enormous impact and continuous improvements of medical cannabis on their son’s health and wellness. Kassidy wishes more people understood the benefits of medical cannabis. “It is medicine. They’re not getting high. They’re not getting drugged. There are pretty much no side effects… It’s safer [than other medications],” she says.

Medical Cannabis & Intractable Pain: Randy's Story

In 1989 while serving in the United States Navy, Randy sustained an injury along his cervical spine from C1 to T4. On September 21, 2016, Randy re-injured his cervical spine while undergoing a patient transport that lacked the proper ventilation equipment. His injuries eventually led to marrow edema from C1 to C3. He also developed degenerative disc disease and degenerative arthritis throughout the entirety of his cervical spine, which are both now progressing down into his thoracic spine into T4.

Before medical cannabis, Randy describes his quality of life as non-existent. The multitude of narcotic drugs used to treat his chronic pain robbed him of the ability to breathe on his own, forcing him to use a ventilator while sleeping due to central sleep apnea caused by the Oxycodone. On a scale from 1 to 10, his pain ranged from 7 to 10 and he was sick to his stomach constantly. He would spend his days sitting in a neutral position, moving as little as possible, to subdue his nausea. More often than not, he would go several days at a time without eating, and driving a car was out of the question. At one point, he was taking over 500 pills per month.

Wanting to find a more natural, sustainable path to relief and diminish his long list of prescription medications, Randy decided to enroll in the Minnesota medical cannabis program. Once he found a physician to certify his condition, he found the process to be much easier than he had initially imagined.

Now, his pain is finally under control and he rates it from 3 to 5 rather than 7 to 10. Randy has been able to eliminate Oxycodone, Etodolac, Nortriptyline, Venlafaxine, Tizanidine, Methocarbamol, Cyclobenzaprine and Lisinopril. Aside from an inhaler and allergy medications, he is free of pain killers and prescription medications. His blood pressure is down to a healthy level and he has been able to lose a healthy amount of excess weight. He no longer has central sleep apnea or peripheral pitting edema in his extremities and his obstructive sleep apnea seems to be going away. Finally, Randy feels as though his body is working the way that it was meant to and beginning to heal itself.

“Marijuana has saved the life I was given,” Randy says, “The horror stories are wrong… it’s definitely worth trying.”

Minnesota Medical Cannabis Program Annual Recertification and Enrollment

As a participant of the Minnesota Medical Cannabis Program, each year you must have your qualifying condition recertified by a Minnesota licensed physician, physician assistant (PA), or an advanced practice registered nurse (APRN) and pay the enrollment fee if you wish to continue to participate in the program.

Here’s what you need to know:

  • As a patient or caregiver, you must resubmit a copy of the certification from your health care practitioner on a yearly basis. Your recertification must be dated within 90 days of submission.
  • Recertification requires an in-person office visit with a health care practitioner who is registered in the Minnesota Medical Cannabis Program. You may recertify your condition up to 90 calendar days prior to your enrollment expiration date.
  • Your enrollment expiration date is based on a rolling year calendar that starts on the day you receive your acceptance e-mail into the program.    
  • You will receive a recertification reminder email at both 60 and 30 days prior to your enrollment expiration date.
  • If you complete the condition recertification and enrollment process prior to your annual enrollment expiration date, you will be automatically reenrolled on your yearly enrollment anniversary date. You will receive an approval e-mail confirmation once your reenrollment application has been reviewed by the Minnesota Department of Health.
  • If you are an approved caregiver in the Minnesota Medical Cannabis Registry, you do not need to complete any type of recertification or reenrollment. Your caregiver’s status is active, as long as the patient in your care is classified in the APPROVED status in the Registry.
  • If you do not complete the recertification process along with your payment before your annual expiration date, you will not be able to visit a Patient Care Center (PCC) or purchase medical cannabis. If you are listed as expired, you must complete the recertification and enrollment process and receive an approval e-mail from the Minnesota Department of Health before you can visit a PCC or purchase medical cannabis.

Questions about the annual recertification and enrollment process? Please comment below, call one of our patient care centers, or send an email to info@leaflinelabs.com.

The Minnesota Medical Cannabis Program: Setting a Gold Standard

Minnesota’s Medical Cannabis Program is unique - but how, exactly? To help break it down, we’ve compiled a list of components that sets the program here in Minnesota apart from those in other states.

No smoked or ingested plant

LeafLine Labs processes plants into botanical extract-based medications.  Doses of cannabinoids (THC and CBD) are formulated, standardized and tested. Medications are formulated based on researched cannabinoid and terpene data, not simply strain-based, user-experience and marketing lingo common in Colorado, Washington and other locations where smoked cannabis is most common. Here, each medication is the same every month and can be dosed accordingly.

Lab tested medication

A third party independent lab tests all medicine to ensure quality and consistency of medications, just like other pharmaceuticals.

Professional medication therapy management

Minnesota Licensed Pharmacists educated in medical cannabinoid therapy and dosing provide care for patients at every LeafLine Labs Care Center. They are specially trained and responsible for objective dosing with our various medication forms, and they are able to adjust dosing and pharmaceutical management based on a patient’s other medications and disease processes.  They can then coordinate with their patient’s physician, similar to the team-based pharmacy approach utilized in most hospitals.

All Medical Cannabis patients are in the state’s research registry

Minnesota is the first state to focus on capturing data related to all patients enrolled in the Medical Cannabis Program. The registry also functions as a checks-and-balances system to ensure patients are only receiving the medication amount that the pharmacist has approved.

Physicians (Health Care Practitioners) certify that patients have qualifying conditions, but aren’t responsible for “recommending” Medical Cannabis

Just like in the hospital inpatient or emergency department setting, physicians provide a patient’s overall medical care but coordinate with the licensed pharmacist who calculates the complex dosing and titration of this unique medicine. In Minnesota, patients must continue to see their physician in order to stay certified in the program which ensures close follow up.

Questions? We’re here to answer them for you. For more information about LeafLine Labs and the Medical Cannabis Program in Minnesota, visit our website here: http://leaflinelabs.com

My Medical Cannabis Story: A Letter From Lee

Hi,

First and foremost I want to thank everyone at LeafLine Labs for all of your life changing work you do. It is not just a job, a task for you, but a mission to help people live with less pain and more happiness.

A few weeks before I had my first dose of Heather, I was in constant pain. I suffer from severe and persistent muscle spasms, extreme pain from spinal stenosis and nerve damage. I also have fibromyalgia and was not having any luck with a variety of prescription medications. I have two beautiful little girls and I was no longer able to hold them without pain and almost immediate intense spasms. Due to narcotic pain meds, I started retaining urine and had to use a catheter. At 33, this was a crushing moment for me. I started to think about my future and what was in store for me. Was this my life going forward? NO! I refused to take 30+ pills a day to get minimal relief. I did my research and decided to pursue getting registered. I was very apprehensive and was worried about what my family would think. Within an hour of my first dose, my back spasms were gone! My pain had decreased from a 9 to a 3! When I told my family they were not only happy for me but very supportive. With a few consults with Ethan, we added the Tangerine for nighttime use and I have never felt better. I owe LeafLine Labs a lifetime of gratitude. I ask those who are hesitant about medical cannabis to do some research on how it is used in Minnesota. You will find that it is a very structured program and has actually helped many many people suffering from life crippling conditions live a much happier life. Thank you, LeafLine Labs! You folks are amazing!

Regards,

Lee